Eficácia da suplementação com probióticos na dermatite atópica pediátrica: uma revisão sistemática
DOI:
https://doi.org/10.34117/bjdv12n7-001Keywords:
dermatite atópica, probióticos, pediatria, imunomodulaçãoAbstract
A dermatite atópica é uma doença inflamatória crônica de alta prevalência na infância, caracterizada por prurido intenso e curso recorrente-remitente. Diante do potencial dos probióticos na modulação da resposta imune, este estudo teve como objetivo avaliar a eficácia da suplementação de probióticos na redução da gravidade clínica da dermatite atópica em lactentes e crianças. Realizou-se uma revisão sistemática conduzida segundo as diretrizes Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), com busca nas bases de dados PubMed/MEDLINE e SciELO. A qualidade metodológica dos estudos incluídos foi avaliada pela escala Downs and Black. Dos 317 estudos identificados, 10 atenderam aos critérios de inclusão. A maioria deles demonstrou redução estatisticamente significativa no índice SCORAD após a suplementação com probióticos. Conclui-se que o uso de probióticos como terapia adjuvante na dermatite atópica pediátrica é promissor, especialmente quanto à redução da gravidade clínica da doença.
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