Um método para determinação voltamétrica simultânea de triptamina e histamina usando eletrodo de carbono vítreo modificado com pontos quânticos de carbono
DOI:
https://doi.org/10.34117/bjdv9n8-160Keywords:
método voltamétrico, eletrodo de carbono vítreo modificado, pontos quânticos de carbono, triptamina, histaminaAbstract
A triptamina e a histamina são aminas biogênicas formadas pela degradação de compostos nitrogenados de matéria orgânica que apresentam potencial risco de desenvolvimento de atividades toxicológicas em seres humanos. Por isso, é fundamental o controle e o monitoramento desses compostos em alimentos e bebidas. A literatura reporta a utilização dos métodos cromatográficos para a determinação dessas aminas biogênicas em baixos níveis de concentração em diversas matrizes. Porém, esses métodos cromatográficos são lentos e apresentam alto consumo de solventes e reagentes prejudiciais à saúde e ao meio ambiente e um alto custo de operação, manutenção e aquisição dos equipamentos e insumos laboratoriais. Para superar esses inconvenientes, uma boa alternativa é o desenvolvimento de métodos voltamétricos para determinação de triptamina e histamina em alimentos em baixos níveis de concentração. Com base nisso, neste trabalho foi desenvolvido com sucesso um novo sensor (o ECV-PQCs/β-CD) e um método voltamétrico rápido, simples, sensível e barato para determinação simultânea de triptamina e histamina. O sensor ECV-PQCs/β-CD utiliza um eletrodo de carbono vítreo (ECV) modificado com pontos quânticos de carbono (PQCs), obtidos a partir do ácido cítrico, e β-ciclodextrina (β-CD). A modificação do ECV consistiu na realização de 8 varreduras de 50 mV s-1 consecutivas em tampão acetato pH 4,5, utilizando voltametria cíclica e uma mistura de pontos quânticos de carbono e β-ciclodextrina. O método voltamétrico proposto apresentou uma faixa linear de resposta e limite de detecção de 12,5 a 25,0 μmol L-1 e 0,25 μmol L-1 para triptamina e 25,0 a 50,0 μmol L-1 e 0,68 μmol L-1 para histamina.
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