Relação entre restrição de crescimento intrauterino com infecção materna por Covid-19
DOI:
https://doi.org/10.34117/bjdv9n6-88Keywords:
Covid-19, restrição de crescimento intrauterinoAbstract
O desenvolvimento de riscos para o crescimento fetal foi reportado na literatura como um possível resultado da sinergia entre a gravidez e a infecção por Covid-19. A pandemia em curso de Covid-19 tem causado um impacto sem precedentes na saúde global, com mais de 647 milhões de casos confirmados e 6 milhões de mortes em todo o mundo até abril de 2023. Dados demonstraram que a transmissão vertical é pouco frequente, no entanto, há observação de lesões placentárias associadas à má perfusão vasculares materna, também encontradas na restrição de crescimento intrauterino (RCIU). Nesse contexto realizou-se uma revisão sistemática da literatura abordando a relação entre RCIU e o acometimento viral por covid-19 (virus SARS-CoV-2) durante o estado gravídico com ênfase nas repercussões fisiopatológicas e clínicas. Seguiu-se o método de revisão sistemática da literatura a partir de uma busca no banco de dados eletrônicos PubMed para a identificação de artigos publicados a partir do ano de 2020 a 2023, utilizou-se os seguintes descritores em saúde: “Covid-19” e “Fetal Growth Restriction”. Os estudos evidenciaram plausibilidade biológica da restrição por acometimento viral, todavia parte significativa dos ensaios clínicos não encontraram diferenças estatisticamente relevantes para a associação. Nesse sentido há necessidade de ensaios clínicos randomizados, bem como com maior número de participantes e acompanhamento longitudinal.
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