PSA alterado e aumento da prevalência do câncer de próstata em militares das forças armadas / PSA altered and increased of prostate cancer prevalence in military of the armed forces

Abstract

Prostate cancer (PCa) is the second type of  most common cancer in men, with a constant increase incidence in Brazil and in the world. In relation to their screening there is a literary divergence as to their need, by the risk of possible complications of subjecting patients to biopsies that diagnose cancers of low agressiveness and that, theoretically, do not require treatment. On the other hand, altered levels of Prostate Specific Antingen (PSA) are found in 85% of men with PCa and the sensitivity of this examnination, combined with the rectal examination, is 95% for diagnosis. The present study aims to identify the relation of altered PSA and the  prevalence increase of PCa in patients of brazilia air force. The methodology consists of a quantitative, restrospective, observational and epidemiological study, performed through 76 medical records between the years of 2016 to 2018, crossing PSA values wtih result of prostate biopsy and rectal examination. Regarding the results, 12% of the analyzed medical records had PSA altered and 55% of these patients had rectal examination discribed as unfavorable (prostatic changes suggestive of malignancy). Furthermore, to pacients with rectal examination unfavorable, 40% had malignancy signs confirmed in prostate biopses. Therefore, it was demonstrated in this study that high levels of PSA has a profound relation with te increase of PCa prevalence, and  when the PSA dosage is associated to rectal examination the relation is more trustworthy.