Perfuração gastrointestinal relacionada a Granulomatose Eosinofílica com Poliangiíte pós-Covid-19 – um relato de caso
DOI:
https://doi.org/10.34119/bjhrv6n2-083Keywords:
Granulomatose eosinofílica com poliangiíte, Churg Strauss, Covid-19, relato de casoAbstract
Introdução: A Granulomatose eosinofílica com poliangiíte (GEPA), anteriormente conhecida como Síndrome de Churg Strauss, é considerada uma doença rara e se caracteriza por uma vasculite necrotizante disseminada, associada com o anticorpo anticitoplasma do neutrófilo (ANCA)4,5. Ocorre infiltração eosinofílica, o qual pode acometer pulmões, coração, rins, tecido nervoso e trato gastrointestinal (TGI) 1, 2, 3 , e que o prognóstico varia de acordo com o sistema acometido 6. Relato do caso: Trata-se de paciente do sexo masculino, 58 anos, que deu entrada em pronto socorro com quadro de abdome perfurativo. O paciente possuía história de asma iniciada na vida adulta, além de internação recente por COVID-19. Os exames laboratoriais demonstravam eosinofilia importante (75% da contagem leucocitária), e o estudo anatomopatológico demonstrou enterite eosinofílica com focos de vasculite eosinofílica. Conclusão: A possibilidade de um diagnóstico de GEPA sempre deve suspeitado em pacientes que apresentam eosinofilia exuberante, principalmente quando associado com história de asma, polipose nasal e parestesias. Um diagnóstico precoce possibilita o início de uma abordagem terapêutica, o que gera significante melhora na qualidade de vida desses pacientes, bem como em seu prognóstico.
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