Biomarkers of angiogenesis: a comparative systematic review between female dog mammary tumors and human breast cancer
DOI:
https://doi.org/10.34188/bjaerv9n1-200Palavras-chave:
biomarkers, immunohistochemistry, breast neoplasm, angiogenesisResumo
Mammary cancer is one of the most common neoplasms in female dogs and, when presenting aggressive behavior, is associated with an increased risk of metastasis and recurrence. Angiogenesis, the formation of new blood vessels,plays a pivotal role in tumor progression and metastatic dissemination. Immunohistochemical evaluation and the identification of angiogenesis-related biomarkers represent important tools for the diagnosis and study of female dog mammary tumors. The aim of this study was to review the available literature on the role of angiogenesis in mammary tumors of female dogs and to compare these findings with human breast cancer.
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