Assessment of renal and hematological effects of chronic Artea® fongicide exposure in Algerian agricultural workers
DOI:
https://doi.org/10.34188/bjaerv7n4-067Palavras-chave:
fungicide, farmer, kidney function, Tifech regionResumo
With the advancement of agriculture, the use of phytosanitary products is growing in popularity, as is their use in the fight against weeds, fungi, and insects. The excessive usage of hazardous chemicals across the country poses a severe risk to soil and water table contamination as well as public health.The purpose of this study was to evaluate the potential effects of extended occupational fungicide exposure on farmers' biomarkers of renal function. In the Souk Ahras wilaya, 60 individuals split into two groups: 30 farmers (exposed group) and 30 subjects who not exposed to agrochemicals on employment in the Tifech commune. Blood samples taken from all agricultural laborers and controls to assess renal function by measuring creatinine, urea, and uric acid. All farm workers and controls received blood samples to measure renal performance by measuring uric acid, urea and creatinine. The results showed a significant and highly significant increase in serum concentrations of uric acid and urea respectively in the farmers compared with the control group (P < 0.01; P < 0.001).However, creatinine showed no significant difference between the groups studied (P > 0.05). According to the current study's findings, farm workers who exposed to fungicide have changes in several biochemical markers, such as uric acid urea, creatinine
Referências
Alengebawy, A ; Taha Abdelkhalek, S ; Qureshi, S. R; Wang, M. Q. (2020). Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications.Toxics, 9, 42.(2020). https://doi.org/10.3390/toxics9030042.
Alfredo, G. C; María, G. H ; Carmen, C. L; Martín-Reina, J ; Aguilera-Velázquez, R; Bautista, J. D; Morales, A. I; Moreno, I. M. (2024). Oxidative stress and renal status of farmers exposed to pesticides in Seville (Spain). Sci. Total Environ., 951, 175180. (2024). https://doi.org/10.1016/j.scitotenv.2024.175180
Andreotti, G; Beane Freeman, L. E; Shearer, J. J; Lerro, C. C; Koutros, S; Parks, C. G. (2020). Occupational pesticide use and risk of renal cell carcinoma in the agricultural health study.Environ. Health Perspect., 128, 67011.(2020). https://doi.org/10.1289/EHP6334
Arciniega, G. M. A. (2020). Health risks due to exposure to chemical pesticides in agricultural workers in the Carrizo Valley, Ahome, Sinaloa. Brazilian Journal of Animal and Environmental Research., 4,3. (2021). DOI: 10.34188/bjaerv4n3-124
Aroonvilairat, S; Kespichayawattana, W; Sornprachum, T; Chaisuriya, P; Siwadune, T; Ratanabanangkoon, K. (2015). Effect of pesticide exposure on immunological, hematological, and biochemical parameters in Thai Orchid farmers—A cross-sectional study. Int. J. Environ. Res. Public Health, 12(6), 5846-5861.(2015).https://doi.org/10.3390/ijerph120605846
Benhamou, H; Khali, M. (2020). Impact of Pesticides on Health and Environment in Algerian Agriculture. J. Environ. Stud., 12(2), 134-149. (2020).
Bonilla, M. A; Gómez, R; Rivera, A; Herrera, D. (2015). Immune and Hematological Assessment in Agricultural Workers Exposed to Fungicides. Environ. Health Perspect.123(4), 301-310. (2015). https://doi.org/10.1289/ehp.1408392
Cortés-Iza, S. C; Rodríguez, A. I; PrietoSuarez, E. (2017). Assessment of Hematological Parameters in Workers Exposed to Organophosphorus Pesticides, Carbamates, and Pyrethroids in Cundinamarca 2016-2017. Rev. Salud Pública.19, 468-474.(2017).
Damayanti, E. F; Setiani, O; Sulistiyani, S. (2019). Association of Pesticides Exposure with Leukocyte Level in Women Farmers in Bandungan Village, Bandungan Sub District, Semarang Regency. Int. J. Health Educ. Soc. 2(11), 26–36 (2019).
Djermouni, L; Abdelaziz, F. (2019). Environmental Persistence and Ecotoxicity of Triazole Fungicides in Algeria. Algerian Environ. J.18(5), 250-270. (2019).
Faustin, P. T. M ; Sharon, A. M ; Edouard, A. N ; Ferdinand, N; Phélix, B. T; Paul, F. M ; Fidelis, C.N. (2018). Evaluation of the Effects of Agro Pesticides Use on Liver and Kidney Function in Farmers from Buea, Cameroon. J. Toxicol.2305764. (2018). https://doi.org/10.1155/2020/2305764
Ige, S. F; Seriki, M. A; Olateju, B. S; Oladipupo, V. A. (2021). Evaluation of age-related changes associated with exposure of Wistar rats to dichlorvos on some haematological parameters. J. Appl. Sci. Environ. Manag. 25(3), 487-491.(2021).
Kaur, R; Mavi, G. K; Raghav, S; Khan, I. (2019). Pesticides classification and its impact on the environment. Int. J. Curr. Microbiol. Appl. Sci .8, 1889–1897. (2019).
Khalifa Desouky, H ; Mokhtar Hassan, R ; Rizka N ; Elsayed Mahmoud Said, H; Mahmoud Abd El-Azeem, R. (2023). Hematological alterations in Egyptian farmers occupationally exposed to pesticides. J. Med. Life Sci.5(3), 135-141. (2023). DOI: 10.21608/jmals.2023.307496
Kim, K. H; Kabir, E &Jahan, S.A. (2017). Exposure to pesticides and the associated human health effects. Sci. Total Environ.575,525–535. (2017).http://doi.org/10.1016/j.scitotenv.2016.09.009
Kumar, S. B; Kumar, J. G; Manoj Kumar, S; Kumar, A. N. (2022). Effects of pesticides on haematological parameters of fish: Recent updates. J. Sci. Res..66(1). (2022). DOI: 10.37398/JSR.2022.660129
López-Gálvez, N; Wagoner, R; Beamer, P; De Zapien, J; Rosales, C. (2018). Migrant Farmworkers’ Exposure to Pesticides in Sonora, Mexico. Int. J. Environ. Res. Public Health.15(12), 2651. (2018). https://doi.org/10.3390/ijerph15122651
Nassar, A. M. K; Salim, Y; Malhat, F. M. (2016). Assessment of pesticide residues in human blood and effects of occupational exposure on hematological and hormonal qualities. J. Environ. Sci..18(5), 250-270 .(2016).
Nuryati, A; Rahardjo, S. S & Murti, B. (2022). Pesticide Exposure and Its Correlation with Hemoglobin and Cholinesterase in Farmers Who Used Pesticide. J. Epidemiol. Public Health.7(3), 380-396. (2022).
Park, S; Islam, M. I; Jeong, J. H; Cho, N. J; Song, H. Y; Lee, E. Y; Gil, H. W. (2019). Hemoperfusion leads to impairment in hemostasis and coagulation process in patients with acute pesticide intoxication. Sci. Rep. 9(1), 1-10. (2019).
Agnandji, P; Ayi-Fanou, L; Cachon, B. F; Mawussi Adjovi, I. S; Ouidoh, L. O. H. (2018). Influence of Pesticide on Biochemical and Hematological Parameters in Beninese Vegetable Farmers. J. Biol. Life Sci.9(1), 65-77. (2018).Doi:10.5296/jbls.v9i1.12461
Ruhul, Q; Zarmin, I; Amin, A; Riaz, M. (2023). Mancozeb-induced cytotoxicity in human erythrocytes: enhanced generation of reactive species, hemoglobin oxidation, diminished antioxidant power, membrane damage and morphological changes. Pestic. Biochem. Physiol.193,105453. (2023). https://doi.org/10.1016/j.pestbp.2023.105453
Shalu, S; Arun, A. U. (2021). Impacts of fungicides on biochemical, haematological, histopathological, development, reproduction, oxidative stress and behavioral aspects: a review. Uttar Pradesh J. Zool., 42(19), 137-145. (2021).
Sharma, P; Huq, A. U; Singh, R. (2014). Cypermethrin-induced reproductive toxicity in the rat is prevented by resveratrol. J. Hum. Reprod. Sci.7, 99-106. (2014). Doi: 10.4103/0974-1208.138867
Sharma, A; Kumar, V; Shahzad, B; Tanveer, M; Sidhu, G. P. S; Handa, N; Kohli, S. K; Yadav, P; Bali, A. S; Parihar, R. D. (2019). Worldwide pesticide usage and its impacts on ecosystem. SN Appl. Sci.1(11), 1446. (2019). https://doi.org/10.1007/s42452-019-1485-1
Shearer, J. I; Sandler, D. P; Andreotti, G; Murata, K; Shrestha, S; Parks, G. P; Liu, D; Alavanja, M. C; Landgren, O; Freeman, L. E. B; Hofmann, J. N. (2021). Pesticide use and kidney function among farmers in the Biomarkers of Exposure and Effect in Agriculture Study. Environ. Res.199,111276. (2021). Doi: 10.1016/j.envres.2021.111276
Sine, H; Bouchriti, Y; Sine, H; Achbani, A.(2023).Comparison of biochemical, haematological and plasmatic butyrylcholinesterase parameters in farmers and non-farmers, Morocco. Adv.Biomed.Res.12(1):181.(2023). DOI: 10.4103/abr.abr_370_22.
Soderland, P; Lovekar, S; Weiner, D. E; Brooks, D. R; Kaufman, J. S. (2010). Chronic kidney disease associated with environmental toxins and exposures. Adv. Chronic Kidney Dis.17, 254–264 (2010).
Srilesin, C; Ruttanapattanakul, J; Amornlertwatana, Y; Watcharakawin, R; Jaikang, C. (2022). Hematological parameters alteration in Thai garlic farmers exposed to mixed pesticides. Indian J. Forensic Med. & Toxicol.16(3), 108-111. (2022).
Taguig, A; Boubsil, S; Abdennour, C; Boulakoud, M. S. (2020). Study of the subacute toxicity of a fungicide on rabbits (Batna region). J. Adv. Pharm. Educ. & Res.10(2), 104-109.145, 274-283. (2020). https://doi.org/10.1016/j.lfs.2015.10.013
Ziada, R. M; Abdulrhman, S. M; Nahas, A. A. (2020). Hepato-nephro-toxicity induced by premium fungicide and protective effect of sesame oil in male rats. Egyptian J. Hosp. Med.81(7), 2445-2450. (2020).
Ziliotto, M; Kulmann-Leal, B; Roitman, A; Bogo Chies, J. A; Ellwanger, J. H. (2023). Pesticide pollution in the Brazilian Pampa: Detrimental impacts on ecosystems and human health in a neglected biome. Pollutants.3, 280–292. (2023).
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