Nodular fasciitis of the submandibular gland: case report

Authors

  • Morejón-Naranjo Luis
  • Moscoso-Veja Edison Danilo
  • Lara-Eras Diana
  • Ortega-Reyes Denisse
  • Peña-Sotomayor Andrés Wilson
  • Nieves-Condoy Jefferson

DOI:

https://doi.org/10.34119/bjhrv9n1-049

Keywords:

nodular fibrosis, connective tissue, submandibular gland

Abstract

Nodular fasciitis is a benign connective tissue tumor characterized by rapidly growing myofibroblastic proliferation with myxoid stroma. It is distinguished from sarcomatous tumors by the absence of cellular atypia. The typical presentation is a painless, mobile, rapidly growing tumor that rarely exceeds 5 cm. The most important differential diagnosis is with sarcomas due to its therapeutic implications. Treatment is resection. In this case report, we present the case of a 70-year-old woman with a rapidly growing tumor in the submandibular region, suspected to be a sarcoma. Wide resection was performed, and the pathology report revealed nodular fibrosis. Follow-up has shown no signs of recurrence.

References

CAMACHO LEONE R, ENCINAS BASCONE A, CORTES JA, MAZO AMOROS C, DE LA SEN CORCUERA Ó. Fascitis nodular en región maxilofacial, un caso clinico. Revista Española de Cirugía Oral y Maxilofacial. 2023;45. https://scielo.isciii.es/pdf/maxi/v45n1/2173-9161-maxi-45-01-46.pdf

MARTÍNEZ PÉREZ F, ARRIBAS GARCÍA I, ÁLVAREZ FLÓREZ M, SERRANO ÁLVAREZ-BUYLLA A, MÉNDEZ MEDINA R, MARTÍNEZ GIMENO C. Fascitis nodular en la región frontal: a propósito de un caso excepcional y revisión de la literatura. Revista Española de Cirugía Oral y Maxilofacial. 2015 Jul;37(3):158–62. https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-05582015000300007

MAULEÓN FERNÁNDEZ C, CHAVARRÍA MUR E, SUÁREZ FERNÁNDEZ R, LÁZARO OCHAITA P, LECONA ECHEVERRÍA M. Fascitis nodular. Actas Dermosifiliogr [Internet]. 2003 Mar 1 [cited 2025 Nov 18];94(2):90–2. Available from: https://www.actasdermo.org/es-fascitis-nodular-articulo-13045923

BALLAL N, HARYADI N, REYES K. Rare cardiac tumour-nodular fasciitis. Cardiol Young. 2024 Apr 29;34(4):933–4. https://pubmed.ncbi.nlm.nih.gov/38282536/

YANG L, HAN F. Intramuscular Nodular Fasciitis of the Masseter. Am J Med Sci. 2021 Nov;362(5):e47–8. https://pubmed.ncbi.nlm.nih.gov/33989564/

SHIMIZU TK, GIBBS P, ORRISON S, MA A. Nodular fasciitis of the breast. Breast J. 2020 May 13;26(5):1054–5. https://pubmed.ncbi.nlm.nih.gov/32052513/

LUNA A, MOLINARI L, BOLLEA GARLATTI LA, FERRARIO D, VOLONTERI V, ROITMAN P, et al. Nodular fasciitis, a forgotten entity. Int J Dermatol. 2019 Feb 6;58(2):190–3. https://pubmed.ncbi.nlm.nih.gov/30191556/

HIDIR Y, ARSLAN HH, GUNHAN O, SATAR B. Case report: nodular fasciitis of the parotid region. J Laryngol Otol. 2011 Dec 5;125(12):1312–4. https://pubmed.ncbi.nlm.nih.gov/21888742/

BARAT M, SOYER P, AUDARD V. Nodular fasciitis: PET/CT and MR imaging features. Diagn Interv Imaging. 2023 Sep;104(9):451–2. https://pubmed.ncbi.nlm.nih.gov/37330412/

LEUNG L, SHU S, CHAN A, CHAN M, CHAN C. Nodular fasciitis: MRI appearance and literature review. Skeletal Radiol. 2002 Jan 30;31(1):9–13. https://pubmed.ncbi.nlm.nih.gov/11807586/

CHIARINI L, LO RUSSO L, FIGURELLI S, PROCACCI P, RUBINI C, LO MUZIO L. Nodular Fasciitis of the Face: Aesthetic Considerations. Aesthetic Plast Surg. 2008 May 11;32(3):560–2. https://pubmed.ncbi.nlm.nih.gov/18330617/

Downloads

Published

01/14/2026

How to Cite

LUIS, M.-N.; DANILO, M.-V. E.; DIANA, L.-E.; DENISSE, O.-R.; WILSON, P.-S. A.; JEFFERSON, N.-C. Nodular fasciitis of the submandibular gland: case report . Brazilian Journal of Health Review, [S. l.], v. 9, n. 1, p. e85072, 2026. DOI: 10.34119/bjhrv9n1-049. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/85072. Acesso em: 21 oct. 2026.

Issue

Section

Original Papers