Myxoid Liposarcoma with Inguino-Retroperitoneal Extension: case report and review of surgical approach

Abstract

Soft tissue sarcomas are a heterogeneous group of connective tissue neoplasms with a low incidence. Myxoid liposarcoma is a rare subtype with a preferential location in the extremities. The gold standard of treatment is wide resection with negative margins for neoplasia. However, unusual locations have different clinical behavior, and their management is limited by a low level of evidence. A 65-year-old man with a lipomatous tumor in the inguinal region who, after marginal resection, showed evidence of myxoid liposarcoma with margins involved by neoplasia. Imaging studies revealed tumor in the inguinal region with retroperitoneal extension. A radical orchiectomy with en bloc resection of the tumor was performed with no evidence of neoplasia in the resected specimen. Close follow-up without adjuvant therapy was decided by a multidisciplinary committee. The approach to a rare soft tissue sarcoma in an unusual region is a challenge in oncological treatment and in the absence of high-quality evidence, the consensus of a multidisciplinary team is necessary to determine the best therapeutic option.