Osteonecrose avascular pós COVID-19
DOI:
https://doi.org/10.34119/bjhrv8n2-388Keywords:
osteonecrose avascular, COVID-19, corticosteróidesAbstract
INTRODUÇÃO: A COVID-19 surgiu em 2019, na China, e logo se espalhou para os demais países, tornando-se uma pandemia. A doença era caracterizada por uma forte inflamação sistêmica, levando as equipes de saúde a prescreverem, cada vez mais, corticosteroides. Contudo, observou-se o aumento da incidência da osteonecrose avascular (NAV) , sendo possivelmente relacionado à pandemia de COVID-19. METODOLOGIA: Trata-se de uma revisão narrativa da literatura, realizada na base de dados PubMed/MEDLINE, com os descritores “Osteonecrosis”, “Avascular necrosis” AND “COVID-19”. Foram selecionados 19 artigos. DESENVOLVIMENTO: A fisiopatologia da COVID-19, com sua tempestade de citocinas e sua ativação da cascata de coagulação possibilita um estado de osteopenia, lesando osteoblastos e osteócitos e prolongando a vida dos osteoclastos. Para diminuir a exacerbação da COVID-19, utiliza-se corticosteróides (CS) das mais diversas formas. Contudo, o uso demasiado de CS pode levar à degradação óssea, sendo a principal causa não traumática de NAV. Assim, uma relação entre a pandemia de COVID-19 e o aumento de casos de NAV pode ser traçada. CONCLUSÃO: O aumento da incidência de NAV aparenta ter relação com a pandemia de COVID-19 e o seu uso exacerbado de corticosteróides. O diagnóstico e tratamento correto são essenciais para mitigar os efeitos da doença. Mais estudos são necessários.
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