Neuralgia Trigeminal: um tipo de dor neuropática - diagnóstico e tratamento
DOI:
https://doi.org/10.34119/bjhrv8n2-150Keywords:
neuralgia trigeminal, tratamento, diagnóstico, anticonvulsivantesAbstract
A neuralgia trigeminal é uma das patologias de dor facial e está entre as mais incapacitantes e que afetam a qualidade de vida dos pacientes. Pode ser classificada como: primária, secundária, idiopática e pós-traumática. O objetivo do presente estudo está em revisar a literatura existente quanto a características clínicas, diagnóstico e tratamento de NT. Para isso, utilizou-se a base de dados PubMed e os descritores Trigeminal Neuralgia, Diagnosis, Dentistry. Obtiveram-se 89 artigos dos quais 30 se encaixaram nos critérios de seleção aplicados. Quanto às características clínicas descreve-se dor unilateral com curta duração e alta intensidade. Predileção pelo gênero feminino. O diagnóstico pode ser difícil e muitas vezes confundido com dor odontogênica. O tratamento comumente proposto é farmacológico com anticonvulsivantes e ocasionalmente cirúrgico. Nota-se que existem poucos estudos acerca do tema. Dos estudos existentes, observa-se unanimidade quanto a dificuldade de diagnóstico e a busca por tratamento conservadores e com menos efeitos colaterais. Contudo, ressalta-se a importância dessa revisão de literatura e de novos estudos referente a esse tipo de dor neuropática, que muitas vezes é subdiagnosticada ou confundida com dor odontogênica.
References
ALLSOP, M. J., TWIDDY, M., GRANT, H., CZOSKI-MURRAY, C., MON-WILLIAMS, M., MUSHTAQ, F., PHILLIPS, N., ZAKRZEWSKA, J. M., & PAVITT, S. (2015). Diagnosis, medication, and surgical management for patients with trigeminal neuralgia: a qualitative study. Acta neurochirurgica, 157(11), 1925–1933. DOI: https://doi.org/10.1007/s00701-015-2515-4
CRUCCU, G., FINNERUP, N. B., JENSEN, T. S., SCHOLZ, J., SINDOU, M., SVENSSON, P., TREEDE, R. D., ZAKRZEWSKA, J. M., & NURMIKKO, T. (2016). Trigeminal neuralgia: New classification and diagnostic grading for practice and research. Neurology, 87(2), 220–228. DOI: https://doi.org/10.1212/WNL.0000000000002840
CHUNG, M. K., WANG, S., OH, S. L., & KIM, Y. S. (2021). Acute and Chronic Pain from Facial Skin and Oral Mucosa: Unique Neurobiology and Challenging Treatment. International journal of molecular sciences, 22(11), 5810. DOI: https://doi.org/10.3390/ijms22115810
COATS, R. O., CROSSLEY, K. L., CONLIN, N., WU, J., ZAKRZEWSKA, J. M., PAVITT, S. H., PHILLIPS, N., & MON-WILLIAMS, M. (2020). Cognitive and sensorimotor function in participants being treated for trigeminal neuralgia pain. The journal of headache and pain, 21(1), 91. DOI: https://doi.org/10.1186/s10194-020-01156-9
DERAFSHI, R., REZAZADEH, F., GHAPANCHI, J., BASANDEH SHARIF, D., & FARZIN, M. (2019). Prevalence of Chronic Orofacial Pain in Elderly Patients Referred to Shiraz Dental School From 2005 to 2017. Anesthesiology and pain medicine, 9(6), e91182. DOI: https://doi.org/10.5812/aapm.91182
FREEMAN, R., EDWARDS, R., BARON, R., BRUEHL, S., CRUCCU, G., DWORKIN, R. H., & HAROUTOUNIAN, S. (2019). AAPT Diagnostic Criteria for Peripheral Neuropathic Pain: Focal and Segmental Disorders. The journal of pain, 20(4), 369–393. DOI: https://doi.org/10.1016/j.jpain.2018.10.002
JACQUES, N., KAROUTSOS, S., MARAIS, L., & NATHAN-DENIZOT, N. (2022). Quality of life after trigeminal nerve block in refractory trigeminal neuralgia: A retrospective cohort study and literature review. The Journal of international medical research, 50(10), 3000605221132027. DOI: https://doi.org/10.1177/03000605221132027
KANDARI, A., DEVAPRASAD, B. A. T. P., HERNANDEZ-RIVERA, P., HERNANDEZ, I. A., & FRIESEN, R. (2024). Botulinum toxin-A as a treatment option for refractory idiopathic trigeminal neuralgia of the ophthalmic branch: a case report and literature review. Oral surgery, oral medicine, oral pathology and oral radiology, 137(5), e73–e82. DOI: https://doi.org/10.1016/j.oooo.2024.02.024
KIM, H., KIM, H. J., JUNG, Y. H., DO, W., & KIM, E. J. (2024). The effect of perineural injection therapy on neuropathic pain: a retrospective study. Journal of dental anesthesia and pain medicine, 24(1), 47–56. DOI: https://doi.org/10.17245/jdapm.2024.24.1.47
MAY, A., BENOLIEL, R., IMAMURA, Y., PIGG, M., BAAD-HANSEN, L., SVENSSON, P., & HOFFMANN, J. (2023). Orofacial pain for clinicians: A review of constant and attack-like facial pain syndromes. Cephalalgia : an international journal of headache, 43(8), 3331024231187160. DOI: https://doi.org/10.1177/03331024231187160
MASCARENHAS, R. J., HAPANGAMA, N. D., MEWS, P. J., BURLAKOTI, A., & RANJITKAR, S. (2019). Orofacial neuralgia associated with a middle cerebral artery aneurysm. Australian dental journal, 64(1), 106–110. DOI: https://doi.org/10.1111/adj.12668
MELO, L. T., PANCHALINGAM, V., CHERKAS, P., CAMPOS, A. R., AVIVI-ARBER, L., & SESSLE, B. J. (2019). (-)-α-Bisabolol reduces nociception and trigeminal central sensitisation in acute orofacial neuropathic pain induced by infraorbital nerve injury. Life sciences, 227, 122–128. DOI: https://doi.org/10.1016/j.lfs.2019.04.032
NOMURA, K., RYU, H., NISHIZAWA, S., YOSHIMI, R., & OIDA, I. (2021). Trigeminal Neuralgia from Acute Sphenoid Sinusitis: Consideration of Anatomical Sphenoid Sinus Variation - A Case Report. Case reports in neurology, 13(1), 171–178. DOI: https://doi.org/10.1159/000513684
NASIR, S. A., TAN, H. L., TAN, H. J., HUSSAINI, H. M., & RAMLI, R. (2017). Stevens-Johnson Syndrome following Failure of Genetic Screening prior to Carbamazepine Prescription. Case reports in dentistry, 2017, 4201357. DOI: https://doi.org/10.1155/2017/4201357
NOMA, N., KITAHARA, I., ISEKI, M., HSU, Y. C., WATANABE, K., NAGANAWA, T., & IMAMURA, Y. (2019). Effects of surgical treatment for classical trigeminal neuralgia with concomitant persistent facial pain. Acta neurologica Taiwanica, 28(1), 17–24.
ONO, Y., SHIMO, T., SHIRAFUJI, Y., HAMADA, T., MASUI, M., OBATA, K., YAO, M., KISHIMOTO, K., & SASAKI, A. (2016). Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia. Case reports in dentistry, 2016, 4605231. DOI: https://doi.org/10.1155/2016/4605231
PEARL, C., MOXLEY, B., PERRY, A., DEMIAN, N., & DALLAIRE-GIROUX, C. (2022). Management of Trigeminal Neuralgia with Botulinum Toxin Type A: Report of Two Cases. Dentistry journal, 10(11), 207. DOI: https://doi.org/10.3390/dj10110207
RÉUS, J. C., PAULETTO, P., VERONEZ, F. C., SOUZA, B. D. M., SCHULDT FILHO, G., STEFANI, C. M., FLORES-MIR, C., & DE LUCA CANTO, G. (2024). Prevalence and management of neuropathic injury caused by dental implant insertion in mandible: a systematic review. Journal of oral & facial pain and headache, 38(2), 25–47. DOI: https://doi.org/10.22514/jofph.2024.012
SHINDE, S., LOHE, V., MOHOD, S., DADGAL, K. V., SHIRBHATE, U., & SOLANKI, D. (2024). Trigeminal Neuralgia Due to Neurovascular Conflict: A Case Report. Cureus, 16(2), e54347. DOI: https://doi.org/10.7759/cureus.54347
Serrera-Figallo, M. A., Ruiz-de-León-Hernández, G., Torres-Lagares, D., Castro-Araya, A., Torres-Ferrerosa, O., Hernández-Pacheco, E., & Gutierrez-Perez, J. L. (2020). Use of Botulinum Toxin in Orofacial Clinical Practice. Toxins, 12(2), 112. DOI: https://doi.org/10.3390/toxins12020112
STEINER, T. J., JENSEN, R., KATSARAVA, Z., LINDE, M., MACGREGOR, E. A., OSIPOVA, V., PAEMELEIRE, K., OLESEN, J., PETERS, M., & MARTELLETTI, P. (2019). Aids to management of headache disorders in primary care (2nd edition) : on behalf of the European Headache Federation and Lifting The Burden: the Global Campaign against Headache. The journal of headache and pain, 20(1), 57. DOI: https://doi.org/10.1186/s10194-018-0899-2
SONG, Y., ZHOU, M., XIONG, J., HUANG, R., SHEN, W., ZHAN, T., XIE, Y., GAO, Y., & XIONG, W. (2024). Effects of carbamazepine on BDNF expression in trigeminal ganglia and serum in rats with trigeminal neuralgia. 卡马西平对三叉神经痛大鼠三叉神经节及血清中BDNF表达变化的影响. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 49(1), 11–20. DOI: https://doi.org/10.11817/j.issn.1672-7347.2024.230278
SÄISÄNEN, L., HUTTUNEN, J., HYPPÖNEN, J., NISSEN, M., KOTIRANTA, U., MERVAALA, E., & FRAUNBERG, M. V. U. Z. (2022). Efficacy and tolerability in patients with chronic facial pain of two consecutive treatment periods of rTMS applied over the facial motor cortex, using protocols differing in stimulation frequency, duration, and train pattern. Neurophysiologie clinique = Clinical neurophysiology, 52(2), 95–108. DOI: https://doi.org/10.1016/j.neucli.2022.03.001
TIRUPATHI, S., & AFNAN, L. (2024). Is trigeminal neuralgia the tip of cancer iceberg: An insight. Journal of cancer research and therapeutics, 20(1), 500–501. DOI: https://doi.org/10.4103/jcrt.jcrt_2488_22
TAKIZAWA, K., TADOKORO, S., OZASA, K., OKADA-OGAWA, A., YOUNG, A., & NOMA, N. (2024). Sixth cranial nerve palsy and trigeminal neuropathic pain due to a space-occupying lesion. Journal of oral science, 66(1), 85–87. DOI: https://doi.org/10.2334/josnusd.23-0155
TRIPATHI, M., SADASHIVA, N., GUPTA, A., JANI, P., PULICKAL, S. J., DEORA, H., KAUR, R., KAUR, P., BATISH, A., MOHINDRA, S., & KUMAR, N. (2020). Please spare my teeth! Dental procedures and trigeminal neuralgia. Surgical neurology international, 11, 455. DOI: https://doi.org/10.25259/SNI_729_2020
TAN, H. L., YAKKAPHAN, P., BEKE, A., & RENTON, T. (2024). Onabotulinum toxin a treatment for posttraumatic trigeminal neuropathic pain: case series and literature review. Journal of oral & facial pain and headache, 38(1), 93–105. DOI: https://doi.org/10.22514/jofph.2024.009
VARDHAN, H., SUSHMITHA, S., NAGAMMAI, N., SARASWATHI, K. (2022). Recurrent Trigeminal Neuralgia: A Case Series and a Review of the Literature. Cureus, 14(2), e22548. DOI: https://doi.org/10.7759/cureus.22548
XIA, S., THORNTON, T., RAVI, V., HAMMAD, Y., ZUNIGA, J. R., & CHHABRA, A. (2024). Efficacy of MR Neurography of Peripheral Trigeminal Nerves: Correlation of Sunderland Grade versus Neurosensory Testing. AJNR. American journal of neuroradiology, 45(3), 335–341. DOI: https://doi.org/10.3174/ajnr.A8120E
ZIEGELER, C., BEIKLER, T., GOSAU, M., & MAY, A. (2021). Idiopathic Facial Pain Syndromes–An Overview and Clinical Implications. Deutsches Arzteblatt international, 118(6), 81–87. DOI: https://doi.org/10.3238/arztebl.m2021.0006
