Leprosy presenting with pruritus mimicking dermatitits artefacta: understanding the significance of recognizing initial clinical manifestations

Authors

  • Ana Carolina Bertazo da Silva
  • Marilda Milanez Morgado de Abreu
  • Gabriela Gasparin
  • Mariana Baptista Angeluci
  • Juliana D’Andrea Molina
  • Marcelo Guimarães Tiezzi

DOI:

https://doi.org/10.34119/bjhrv8n1-026

Keywords:

differential diagnosis, diagnostic errors, leprosy, itching

Abstract

Leprosy is a chronic, curable, infectious granulomatous disease caused by acid-fast bacilli (AFB) from the Mycobacterium leprae complex. Early diagnosis allows for appropriate treatment, preventing transmission and potential neurological sequelae. This report describes a case of a 67-year-old male patient who has presented with complaints of "allergy," experiencing itching in the left upper limb, accompanied by scratches, with skin lesions suggestive of factitious dermatitis. Months after treatment, he developed new ulcerated lesions and was diagnosed, through clinical and histopathological examination, as having dimorphic-Virchowian leprosy. In this sense, the clinical diagnosis of leprosy can be significantly challenging, especially considering its complex pathology, diverse symptoms, delayed progression, and varying immune responses.

References

ARAÚJO, M. G. Leprosy in Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 36, n. 3, p. 373–382, 2004. DOI: 10.1590/S0037-86822003000300010.

BROWNE, S. G. Some less common neurological findings in leprosy. Journal of Neurological Sciences, v. 2, n. 3, p. 253–261, 1965. DOI: 10.1016/0022-510X(65)90109-7.

CHEN, K. H.; LIN, C. Y.; SU, S. B.; CHEN, K. T. Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management. Journal of Tropical Medicine, v. 2022, 4 jul. 2022. DOI: 10.1155/2022/8652062. PMID: 35832335.

DATHI. Indicadores Hanseníase. Disponível em: http://indicadoreshanseniase.aids.gov.br/. Acesso em: 1 ago. 2024.

FROES, L. A. R.; SOTTO, M. N.; TRINDADE, M. A. B. Leprosy: clinical and immunopathological characteristics. Anais Brasileiros de Dermatologia, v. 97, n. 3, p. 338–347, 2022. DOI: 10.1016/j.abd.2021.08.006.

HUNDEMER, M.; WAN, C. R. Disfiguring facial lesions and loss of sensation. JAAPA, v. 31, n. 1, p. 27–29, 2018. DOI: 10.1097/01.JAA.0000526775.98315.5a. PMID: 29278562.

Downloads

Published

01/06/2025

How to Cite

SILVA, A. C. B. da; ABREU, M. M. M. de; GASPARIN, G.; ANGELUCI, M. B.; MOLINA, J. D.; TIEZZI, M. G. Leprosy presenting with pruritus mimicking dermatitits artefacta: understanding the significance of recognizing initial clinical manifestations. Brazilian Journal of Health Review, [S. l.], v. 8, n. 1, p. e76462, 2025. DOI: 10.34119/bjhrv8n1-026. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/76462. Acesso em: 24 oct. 2026.

Issue

Section

Original Papers