Aplicação clínica da terapia fotodinâmica antimicrobiana em odontologia: uma revisão narrativa da literatura e avanços recentes
DOI:
https://doi.org/10.34119/bjhrv7n9-467Keywords:
terapia fotodinâmica antimicrobiana, aPDT, terapia a laser, manifestações orais, fotossensibilizadorAbstract
O uso da terapia fotodinâmica antimicrobiana (aPDT, sigla em inglês para antimicrobial Photodynamic Therapy) é uma técnica promissora para o tratamento de infecções orais em diversas áreas da odontologia. A aPDT baseia-se na ativação de um fotossensibilizador por uma fonte de luz em um comprimento de onda específico, que resulta na geração de espécies reativas de oxigênio (ROS) capazes de destruir seletivamente células microbianas. Esse método oferece várias vantagens, incluindo a eliminação de microrganismos resistentes e a redução dos efeitos colaterais associados aos tratamentos antimicrobianos convencionais. Os dados foram coletados utilizando os descritores: "Photodynamic Therapy" OR "Antimicrobial Photodynamic Therapy" AND "dentistry" na base de dados PubMed. Os artigos selecionados foram publicados entre 2021 e agosto de 2024. A partir de uma seleção de 51 estudos, são discutidas as aplicações da aPDT em diferentes indicações na odontologia. A revisão apresenta dados sobre a eficácia do tratamento, tipos de fotossensibilizadores utilizados, métodos de aplicação e resultados clínicos. A versatilidade, eficácia e segurança da aPDT a tornam uma alternativa relevante, complementando tratamentos odontológicos convencionais.
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