Correlation between Pancreatic Cancer and Diabetes - brief review of the last 5 years

Abstract

Diabetes mellitus is a group of metabolic diseases defined by persistent hyperglycemia. Severe hyperglycemia leads to classic symptoms such as polyuria, polydipsia, fatigue, and decreased performance. This condition presents, different classifications considering its possible etiologies, being four subtypes: type 1, type 2, gestational and other specific forms of diabetes type 3c. It is suggested that there is a strong association between diabetes mellitus (especially type 2 diabetes mellitus) and carcinogenesis, but this correlation is still underestimated during the diagnosis of diabetes. This paper aims to review the literature on the PubMed search platform for papers from the last five years on the correlation between pancreatic cancer and diabetes; through the adoption of specific descriptors and rigorous selection criteria of the selected articles to be used as a basis, and thus a total of twenty two articles fit to carry out this work. Based on the current literature, several studies have suggested that diabetes mellitus and cancer are often coexisting diseases, but they are rarely diagnosed concurrently and consequently make treatment difficult and the prognosis tends to be unfavorable, which makes greater disclosure about the correlation essential. among such diseases, aiming at a better diagnosis in a systematic way, and thus making the patient's prognosis more reliable.