Abordagens emergentes para o tratamento da obesidade e síndrome metabólica
DOI:
https://doi.org/10.34119/bjhrv6n3-240Keywords:
obesidade, síndrome metabólica, terapias emergentes, tratamento, intervenções farmacológicasAbstract
A obesidade e a síndrome metabólica (SM) representam desafios significativos para a saúde pública mundial, devido à sua alta prevalência e associação com doenças cardiovasculares e diabetes tipo 2. Esta revisão analisa as abordagens emergentes para o tratamento da obesidade e SM, incluindo intervenções farmacológicas, terapêuticas comportamentais, dispositivos médicos e terapias em desenvolvimento. Dentre as intervenções farmacológicas, os agonistas do receptor de peptídeo-1 semelhante ao glucagon (GLP-1) têm mostrado resultados promissores. As terapias comportamentais, como a terapia cognitivo-comportamental e o uso de aplicativos para smartphones, têm sido exploradas para melhorar o controle do peso e os fatores de risco cardiometabólicos. Dispositivos médicos, como balão intragástrico e estimulação do nervo vago, apresentam alternativas menos invasivas à cirurgia bariátrica. Terapias em desenvolvimento, como a manipulação da microbiota intestinal e terapias celulares e genéticas, têm potencial para abordar os mecanismos subjacentes à obesidade e SM. Mais pesquisas são necessárias para determinar a eficácia a longo prazo e a segurança dessas abordagens e identificar as melhores práticas para tratamentos individualizados.
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