Intralesional administration of meglumine antimoniate (MA) as an alternative treatment for cutaneous leishmaniasis: a case report
DOI:
https://doi.org/10.34119/bjhrv6n1-259Keywords:
Leishmania, glucantime, neglected diseaseAbstract
Cutaneous leishmaniasis (CL) is not a life-threatening condition, the treatment of which can cause serious adverse effects and sometimes lead to death. In this study, we report a case of success in the treatment of LC of a 2.5 cm lesion located in the neck region of a 22-year-old man treated with intralesional meglumine antiomoniate (IL-MA) without adverse effects and without recurrence or complications after 18 months of follow-up. The results suggest that the treatment of CL lesions with IL-MA is simple, efficient and safe.
References
BARÇANTE, T.A., et al., 2019. Use of the polymerase chain reaction for the diagnosis of American Tegumentary Leishmaniasis. An. Bras. Dermatol. v. 94, n. 1, p. 113-114. Avaiable from https://doi.org/10.1590/abd1806-4841.20197929>
BRASIL, MINISTÉRIO DA SAÚDE, SECRETARIA DE VIGILÂNCIA EM SAÚDE. Manual de vigilância a leishmaniose tegumentar. Brasília: Ministério da Saúde, 2017. 189 p.:il. Avaiable from <https://bvsms.saude.gov.br/bvs/publicacoes/manual_vigilancia_leishmaniose_tegumentar.pdf>.
DE OLIVEIRA DUQUE, M.C., et al. 2019. Comparison between systemic and intralesional meglumine antimoniate therapy in a primary health care unit. Acta Trop. v. 193, p. 176-182. Avaiable from: <https://doi.org/10.1016/j.actatropica.2019.03.007>
SANTIAGO, M.A., et al. 2019. Successful treatment of cutaneous leishmaniasis with intralesional meglumine antimoniate: A case series. Rev. Soc. Bras. Med. Trop. v. 52. Avaiable from <https://doi.org/10.1590/0037-8682-0211-2018>.
SILVA, R.E., et al. 2018. Towards a standard protocol for antimony intralesional infiltration technique for cutaneous leishmaniasis treatment. Mem. Inst. Oswaldo Cruz, Rio de Janeiro , v. 113, n. 2, p. 71-79. Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000200071&lng=en&nrm=iso>. access on 13 Sept. 2019. http://dx.doi.org/10.1590/0074-027601700125.
WHO - World Health Organization. Control of the leishmaniases. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases. Geneva: WHO; 22-26 March 2010. Available from: http://apps.who.int/iris/bitstream/10665/44412/1/WHO_TRS_949_eng.pdf. [ Links ]


