Os subtipos sanguíneos do sistema abo e a suscetibilidade ao Sars-Cov-2

Authors

  • Eduarda Matos Cavalcante
  • Jenifer Silva de Souza
  • Ângela Isabel P. Eugenio
  • João Carlos Pina Faria

DOI:

https://doi.org/10.34119/bjhrv6n1-059

Keywords:

“Infecção pelo SARS-CoV-2, “Covid-19”, “Sistema ABO de Grupos Sanguíneos”

Abstract

Este artigo de revisão integrativa analisa a associação entre os subtipos sanguíneos do sistema ABO e o contágio por SARS-CoV-2 e suas interferências clínicas. Trata-se de uma revisão baseada em 34 estudos, do período de abril de 2020 a agosto de 2022, a partir das bases de dados SciELO, MEDLINE/PubMed e Scopus. Os manuscritos selecionados foram apresentados em tabelas para maior entendimento. Entre os estudos avaliados, 26 observaram associação entre os grupos sanguíneos e o contágio por SARS-CoV-2. O grupo sanguíneo O sugere proteção contra o vírus. Foram propostos alguns mecanismos para justificar a proteção do grupo O em relação à infecção pelo SARS-CoV-2. 

References

OPAS, ORGANIZAÇÃO PAN AMERICANA DA SAÚDE. Histórico da pandemia de Covid-19. OPAS. 2020. Disponível em: https://www.paho.org/pt/covid19/historico-da-pandemia-covid-19. Acesso em: 23 nov. 2022.

BENVENUTO, D; GIOVANETTI, M; CICCOZZI, A; et al. The 2019‐new coronavirus epidemic: Evidence for virus evolution. PMC, PubMed. 2020. Disponível em: doi: https://doi.org/10.1002%2Fjmv.25688 Acesso em: 26 nov. 2022.

OMS, ORGANIZAÇÃO MUNDIAL DA SAÚDE. 2022 Disponivel em: https://covid19.who.int/ Acesso em 26 nov. 2022.

BATISSOCO, Ana Carla; NOVARETT, Marcia Cristina. Aspectos moleculares do Sistema Sanguíneo ABO. SCIELO. 2003. Disponível em: https://doi.org/10.1590/S1516-84842003000100008. Acesso em: 23 nov. 2022.

CHENG, Y ; CHENG, G; CHUI, CH, et al. ABO blood group and susceptibility to severe acute respiratory syndrome. JAMA. 2005. Disponível em: 10.1001/jama.293.12.1450-c Acesso em 26 nov. 2022.

POZZOBON, Rochele. Expressão de antígenos do sistema sanguíneo ABO associados à predisposição e ao prognóstico de câncer de mama. Dissertação (Ciências Farmacêuticas) - Universidade Federal de Santa Maria,RS, 2010. Disponível em: https://repositorio.ufsm.br/handle/1/5933 Acesso em 26 nov. 2022.

XU, LI. et al. Association between ABO blood group and HCV-related hepatocellular carcinoma risk in China. PUBMED. 2016. Disponível em: 10.1097/MD.0000000000005587. Acesso em: 23 nov. 2022.

ZHANG, XF, e al. Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections. PLoS One. 2013. Disponível em: https://doi.org/10.1371/journal.pone.0069379. Acesso em: 26 nov. 2022.

DAI X. ABO blood group predisposes to COVID-19 severity and cardiovascular diseases. European journal of preventive cardiology. 2020. Disponível em: https://doi.org/10.1177/2047487320922370. Acesso em: 23 nov. 2022.

YAMAMOTO, F; MUNIZ-DIAZ, E. Blood group ABO polymorphism inhibits SARS-CoV-2 infection and affects COVID-19 progression. Vox sanguinis. 2021. Disponível em: https://doi.org/10.1111/vox.13004. Acesso em: 23 nov. 2022.

ZHAO, Jiao. et al. Relationship between the ABO Blood Group and the COVID-19 Susceptibility. MedRxiv. 2020. Disponível em: https://doi.org/10.1101/2020.03.11.20031096. Acesso em: 23 nov. 2022.

WU,Y; FENG, Z; LI, P; YU, Q. Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19. ELSEVIER. 2020. Disponível em: https://doi.org/10.1016/j.cca.2020.06.026 Acesso em: 23 nov. 2022.

GOKER, H, et al. The effects of blood group types on the risk of COVID-19 infection and its clinical outcome. PUBMED. 2020. Disponível em: https://journals.tubitak.gov.tr/medical/index.htm Acesso em: 23 nov. 2022.

RAY,J, et al. Association Between ABO and Rh Blood Groups and SARS-CoV-2 Infection or Severe COVID-19 Illness : A Population-Based Cohort Study. PUBMED. 2020. Disponível em: https://doi.org/10.7326/M20-4511 Acesso em: 23 nov. 2022.

FAN, Q, et al. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. PUBMED. 2020. Disponível em: https://doi.org/10.3389/fcimb.2020.00404 Acesso em: 23 nov. 2022.

ZIETZ, M; ZUCKER, J; TATONETTI, N. Associations between blood type and COVID-19 infection, intubation, and death. PUBMED. 2020. Disponível em: https://doi.org/10.1038/s41467-020-19623-x Acesso em: 26 nov. 2022.

HOLLAND, R, et al. The association of ABO blood group with indices of disease

severity and multiorgan dysfunction in COVID-19. PUBMED. 2020. Disponível em: https://doi.org/10.1182/bloodadvances.2020002623 Acesso em: 26 nov. 2022.

MUNIZ-DIAZ, E, et al. Relationship between the ABO blood group and COVID-19 susceptibility, severity and mortality in two cohorts of patients. PUBMED. 2020. Disponível em: https://www.bloodtransfusion.it/articolo.aspx?idart=003350&idriv=000158&idart=003350&idriv=000158 Acesso em: 26 nov. 2022.

LEAF, R, et al. ABO phenotype and death in critically ill patients with COVID-19. PUBMED. 2020. Disponível em: https://doi.org/10.1111/bjh.16984 Acesso em: 26 nov. 2022.

BARNKOB, M, et al. Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. PUBMED. 2020. Disponível em: https://doi.org/10.1182/bloodadvances.2020002657 Acesso em: 26 nov. 2022.

DELEERS, M, et al. Covid-19 and blood groups: ABO antibody levels may also matter. PUBMED. 2020. Disponível em: https://doi.org/10.1016/j.ijid.2020.12.025 Acesso em: 26 nov. 2022.

YALAOUI, S, et al. ABO blood groups and risk of covid-19, PUBMED. 2020. Disponível em: La Tunisie medicale, 98(12), 888–891. Acesso em: 26 nov. 2022.

YAYLACI, S, et al. The effect of abo and rh blood group antigens on admission to intensive care unit and mortality in patients with COVID-19 infection. SCIELO. 2020. Disponível em: https://doi.org/10.1590/1806-9282.66.S2.86 Acesso em: 26 nov. 2022.

LATZ, C, et al. Blood type and outcomes in patients with COVID-19. PUBMED. 2020. Disponível em: https://link.springer.com/article/10.1007/s00277-020-04169-1 Acesso em: 26 nov. 2022.

KHALIL, A; FEGHALI, R; HASSOUN, M. The Lebanese COVID-19 Cohort; A Challenge for the ABO Blood Group System. PUBMED. 2020. Disponível em: https://doi.org/10.3389/fmed.2020.585341 Acesso em: 26 nov. 2022.

BHANDARI, P, et al. Analysis of ABO and Rh Blood Type Association With Acute COVID-19 Infection in Hospitalized Patients: A Superficial Association Among a Multitude of Established Confounders. PUBMED. 2020. Disponível em: https://doi.org/10.14740/jocmr4382 Acesso em: 26 nov. 2022.

KOLIN, D; et al. Clinical, regional, and genetic characteristics of Covid-19 patients from UK Biobank. PUBMED. 2020. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241264 Acesso em: 26 nov. 2022.

SOLMAZ, İ; ARAÇ, S. ABO blood groups in COVID-19 patients; Cross-sectional study. PUBMED. 2020. Disponível em: https://doi.org/10.1111/ijcp.13927 Acesso em: 26 nov. 2022.

NAUFFAL, V; et al. Association of ABO blood group type with cardiovascular events in COVID-19. PUBMED. 2021. Disponível em: https://link.springer.com/article/10.1007/s11239-020-02364-5 Acesso em: 26 nov. 2022.

TAHA, S; et al. Individuals with a Rh-positive but not Rh-negative blood group are more vulnerable to SARS-CoV-2 infection: demographics and trend study on COVID-19 cases in Sudan. PUBMED. 2020. Disponível em: https://www.clinicalkey.com/service/content/pdf/watermarked/1-s2.0-S2052297520301153.pdf?locale=pt_BR&searchIndex= Acesso em: 26 nov. 2022.

SILVA-FILHO, J. C; MELO, C; OLIVEIRA, J. L. The influence of ABO blood groups on COVID-19 susceptibility and severity: A molecular hypothesis based on carbohydrate- carbohydrate interactions. ELSEVIER. 2020. Disponível em: https://www.sciencedirect.com/science/article/pii/S0306987720322581?via%3Dihub Acesso em: 26 nov. 2022.

LIU, Y; et al. Association between the dynamics of the COVID-19 epidemic and ABO blood type distribution. PUBMED. 2021. Disponível em: https://doi.org/10.1017/S0950268821000030 Acesso em: 26 nov. 2022.

Nalbant, A; et al. Association of ABO blood group and age with COVID-19 positive test. SCIELO. 2021. Disponível em: https://doi.org/10.1590/1806-9282.67.Suppl1.20200703 Acesso em: 26 nov. 2022.

ALMADHI, M; et al. The effect of ABO blood group and antibody class on the risk of COVID-19 infection and severity of clinical outcomes. PUBMED. 2021. Disponível em: https://doi.org/10.1038/s41598-021-84810-9 Acesso em: 26 nov. 2022.

EL-SHITANY, N; et al. The Impact of ABO Blood Grouping on COVID-19 Vulnerability and Seriousness: A Retrospective Cross-Sectional Controlled Study among the Arab Community. PUBMED. 2021. disponível em: https://www.mdpi.com/1660-4601/18/1/276 Acesso em: 26 nov. 2022.

RAHIM, F; et al. ABO / Rh-D Blood types and susceptibility to Corona Virus Disease-19 in Peshawar, Pakistan. PUBMED. 2021. Disponível em: http://pjms.org.pk/index.php/pjms/article/view/3655 Acesso em: 26 nov. 2022.

MULLINS, J; et al. The association of ABO blood type with the risk and severity of COVID-19 infection. PUBMED. 2021. disponível em: PMID: 33796389 Acesso em: 26 nov. 2022.

ABDOLLAHI, Alireza; et al. The Novel Coronavirus SARS-CoV-2 Vulnerability Association with ABO/Rh Blood Types. PUBMED. 2020. disponível em: https://ijp.iranpath.org/article_39842.html Acesso em: 26 nov. 2022.

KOTILA, T. R; et al. Association of the ABO blood group with SARS-CoV-2 infection in a community with low infection rate. PUBMED. 2021. Disponível em: https://doi.org/10.1111/vox.13077 Acesso em: 26 nov. 2022.

COLUK, Y; et al. Association of Blood Subgroups With PCR Test Positivity and Lung Involvement in Patients With COVID-19. PUBMED. 2021. Disponível em: https://www.cureus.com/articles/55271-association-of-blood-subgroups-with-pcr-test-positivity-and-lung-involvement-in-patients-with-covid-19 Acesso em: 26 nov. 2022.

AL-ANSARI, R. Y; et al. ABO in Correlation to the Requirement of Mechanical Ventilation and Mortality in Critically Ill Patients With COVID-19. PUBMED. 2021. Disponível em: https://www.thejh.org/index.php/JH/article/view/821 Acesso em: 26 nov. 2022.

BADEDI, M; MAKRAMI, A; ALNAMI, A. Co-morbidity and blood group type risk in coronavirus disease 2019 patients: A case-control study. ELSEVIER. 2021. Disponível em: https://www.clinicalkey.com/service/content/pdf/watermarked/1-s2.0-S1876034121000046.pdf?locale=pt_BR&searchIndex= Acesso em: 26 nov. 2022.

SZYMANSKI, J; et al. ABO blood type association with SARS-CoV-2 infection mortality: A single-center population in New York City. PUBMED. 2021. Disponível em: https://onlinelibrary.wiley.com/doi/10.1111/trf.16339 Acesso em: 26 nov. 2022.

TORRES-ALARCON, C. G; et al. Blood system ABO antigens as risk factor for severity of SARS-CoV-2 infection. PUBMED. 2021. Disponível em: https://www.gacetamedicademexico.com/frame_eng.php?id=569 Acesso em: 26 nov. 2022.

DE FREITAS DUTRA, V; et al. Anti-A and SARS-CoV-2: an intriguing association. PUBMED. 2021. Disponível em: https://doi.org/10.1111/vox.13044 Acesso em: 26 nov. 2022.

BROX R, ACHENBACH S, HACKSTEIN H. Detection of SARS-CoV-2-independent immunoregulatory activity of COVID-19 convalescent plasma. Transfusion. PUBMED. 2021 Disponivel em: doi: 10.1111/trf.16685 Acesso em: 26 nov. 2022.

Alemany A, Millat-Martinez P, Corbacho-Monné M, et al. High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial. Lancet Respir Med. 2022 Disponivel em: doi: 10.1016/S2213-2600(21)00545-2 Acesso em: 26 nov. 2022.

Published

01/11/2023

How to Cite

CAVALCANTE, E. M.; DE SOUZA, J. S.; P. EUGENIO, Ângela I.; FARIA, J. C. P. Os subtipos sanguíneos do sistema abo e a suscetibilidade ao Sars-Cov-2. Brazilian Journal of Health Review, [S. l.], v. 6, n. 1, p. 770–782, 2023. DOI: 10.34119/bjhrv6n1-059. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/56211. Acesso em: 17 oct. 2026.

Issue

Section

Original Papers