Chorea as the first manifestation of systemic Lupus erythematosus: a case report

Authors

  • Rebecca de Souza Costa
  • Dalila Iari Silva Barbosa
  • Thais Chab Campano Latorre
  • José Eduardo Martinez

DOI:

https://doi.org/10.34119/bjhrv6n1-001

Keywords:

systemic Lupus erythematosus, Chorea, central nervous system, antiphospholipid antibodies

Abstract

Systemic Lupus Erythematosus (SLE) is a disorder of the immune system with a wide range of symptoms. The involvement of kidneys, lungs and central nervous system (CNS) denotes a more severe character and worse prognosis. Several neurological and psychiatric manifestations may be present, the most common being convulsion, neuropathies and acute confusional state, but chorea is seen in less than 2% of patients. Recent studies show that antiphospholipid antibodies (aPL) correlate with the appearance of chorea in SLE.

References

Marianthi Kiriakidou , Cathy Lee Ching Systemic Lupus Erythematosus. Ann Intern Med. 2020 Jun 2;172(11):ITC81-ITC96. doi: 10.7326/AITC202006020.

John G Hanly. Diagnosis and management of neuropsychiatric SLE. Nat Rev Rheumatol. 2014 Jun;10(6):338-47. doi:10.1038/nrrheum.2014.15.

Avcin T, Benseler SM, Tyrrell PN, Cucnik S, Silverman ED. A followup study of antiphospholipid antibodies and associated neuropsychiatric manifestations in 137 children with systemic lupus erythematosus. Arthritis Rheum. 2008 Feb 15;59(2):206-13. doi: 10.1002/art.23334. PMID: 18240179.

Sonu SK, Ng JCH, Chua SM, Kumar MP, De Silva D. Chorea precipitated by phototherapy as initial presentation of systemic lupus erythematosus. Ann Acad Med Singap. 2021 Oct;50(10):788-790. doi: 10.47102/annals-acadmedsg.2021137. PMID: 34755174.

Baizabal-Carvallo JF, Alonso-Juarez M, Koslowski M. Chorea in systemic lupus erythematosus. J Clin Rheumatol. 2011 Mar;17(2):69-72. doi: 10.1097/RHU.0b013e31820e7c8d. PMID: 21325962.

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Published

2023-01-02

How to Cite

COSTA, R. de S.; BARBOSA, D. I. S.; LATORRE, T. C. C.; MARTINEZ, J. E. Chorea as the first manifestation of systemic Lupus erythematosus: a case report. Brazilian Journal of Health Review, [S. l.], v. 6, n. 1, p. 02–05, 2023. DOI: 10.34119/bjhrv6n1-001. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/55892. Acesso em: 19 may. 2024.

Issue

Section

Original Papers