Evidências sobre o tratamento cirúrgico do melanoma metastático / Evidence on surgical treatment of metastatic melanoma
DOI:
https://doi.org/10.34119/bjhrv5n1-103Keywords:
Melanoma, Metástase, Tratamento cirúrgico.Abstract
A incidência de melanoma cutâneo tem aumentado nas últimas décadas, enquanto os pacientes com melanoma em estágio inicial, I ou II, têm um prognóstico favorável com a cirurgia como o principal e único tratamento necessário, e aqueles com melanoma em estágio III ou IV têm prognóstico pior. A cirurgia continua a ter um papel fundamental no tratamento em face dessas terapias sistêmicas mais eficazes para melanoma avançado e pode estar associada a uma melhor sobrevida em longo prazo. Os pacientes com suspeita de doença metastática à distância devem ser submetidos a uma avaliação abrangente para avaliar os locais e a carga da doença antes de considerar a cirurgia. O fígado e o SNC são locais comuns e frequentemente a causa de morte por melanoma metastático. Outros locais incluem pele, pulmão, nódulos linfáticos, trato gastrointestinal, glândula adrenal, pâncreas, baço e osso.
References
Bello DM. Indications for the surgical resection of stage IV disease. J Surg Oncol 2019; 119:249.
Enomoto LM, Levine EA, Shen P, Votanopoulos KI. Role of Surgery for Metastatic Melanoma. Surg Clin North Am 2020; 100:127.
O'Neill CH, McMasters KM, Egger ME. Role of Surgery in Stage IV Melanoma. Surg Oncol Clin N Am 2020; 29:485.
Gershenwald JE, Scolyer RA, Hess KR, et al. Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin 2017; 67:472.
Howard JH, Thompson JF, Mozzillo N, et al. Metastasectomy for distant metastatic melanoma: analysis of data from the first Multicenter Selective Lymphadenectomy Trial (MSLT-I). Ann Surg Oncol 2012; 19:2547.
Leo F, Cagini L, Rocmans P, et al. Lung metastases from melanoma: when is surgical treatment warranted? Br J Cancer 2000; 83:569.
Leung AM, Hari DM, Morton DL. Surgery for distant melanoma metastasis. Cancer J 2012; 18:176.
Wang Y, Ren S, Gong X, et al. Prognostic factors for postoperative survival in melanoma patients with bone metastasis. Medicine (Baltimore) 2021; 100:e24558.
Sampson JH, Carter JH Jr, Friedman AH, Seigler HF. Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma. J Neurosurg 1998; 88:11.
Glitza IC, Smalley KSM, Brastianos PK, et al. Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions. Pigment Cell Melanoma Res 2020; 33:527.
Sosman JA, Moon J, Tuthill RJ, et al. A phase 2 trial of complete resection for stage IV melanoma: results of Southwest Oncology Group Clinical Trial S9430. Cancer 2011; 117:4740.
Bello DM, Panageas KS, Hollmann T, et al. Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade. Ann Surg Oncol 2020; 27:1180.
Zimmer L, Livingstone E, Hassel JC, et al. Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet 2020; 395:1558.
Hanna TP, Chauvin C, Miao Q, et al. Clinical Outcomes After Pulmonary Metastasectomy for Melanoma: A Population-Based Study. Ann Thorac Surg 2018; 106:1675.
Sharma A, Duijm M, Oomen-de Hoop E, et al. Survival and prognostic factors of pulmonary oligometastases treated with stereotactic body radiotherapy. Acta Oncol 2019; 58:74.
Gallino G, Maurichi A, Patuzzo R, et al. Surgical treatment of melanoma metastases to the small bowel: A single cancer referral center real-life experience. Eur J Surg Oncol 2021; 47:409.
Mittendorf EA, Lim SJ, Schacherer CW, et al. Melanoma adrenal metastasis: natural history and surgical management. Am J Surg 2008; 195:363.
Ollila DW, Hsueh EC, Stern SL, Morton DL. Metastasectomy for recurrent stage IV melanoma. J Surg Oncol 1999; 71:209.


