Encefalopatia relacionada a covid-19: Uma revisão narrativa / Covid-19 related encephalopathy: A narrative review
DOI:
https://doi.org/10.34119/bjhrv4n5-214Keywords:
COVID-19, Encefalopatia e Brain Disease.Abstract
Introdução: O “novo coronavírus” da Síndrome Respiratória Aguda Grave 2 (SARS-CoV-2) foi descoberto na China em 2019, sendo responsável por causar o COVID-19. Essa doença pode afetar os sistemas respiratório, gastrointestinal e neurológico. Quanto às afecções neurológicas, os sintomas envolvem convulsões febris e encefalite, sendo a encefalopatia uma das principais manifestações do SNC nesses pacientes com a doença em fase avançada. Metodologia: Revisão sistemática nas bases de dados PubMed, SciELO e periódicos CAPES empregando-se os descritores encefalopatia e COVID-19. Resultados: Importantes associações foram encontradas entre a encefalopatia e os pacientes infectados com o coronavírus. Nesse sentido, mais da metade desses pacientes receberam o diagnóstico dessa afecção neurológica. Discussão: No COVID-19, a encefalopatia predomina como manifestação neurológica quando comparada ao AVC e encefalite. A resposta inflamatória contra o vírus faz parte da fisiopatologia da doença dando origem a alterações como hipóxia, isquemia e alterações metabólicas. Além disso, sua manifestação clínica envolve disfunção cerebral difusa, confusão mental, cefaléia, convulsões e delirium. Conclusão: Os pacientes infectados com a doença do coronavírus possuem vários sinais e sintomas neurológicos, sendo a encefalopatia mais incidente, fazendo-se necessário cuidados intensivos.
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