O uso de corticoterapia sistêmica na infecção pelo SARS-CoV-2 / The use of corticosteroids in the SARS-CoV-2 infeccion
DOI:
https://doi.org/10.34119/bjhrv4n4-228Keywords:
Corticosteroides. Coronavírus. InfecçãoAbstract
INTRODUÇÃO: O uso de corticosteroides foi pensado como tratamento na infecção pelo SARS-CoV-2 devido ao seu efeito imunomodulador e anti-inflamatório. Isso foi considerado pois, a tempestade de citocinas é uma das principais causas de exacerbação da doença e progressão para síndrome de desconforto respiratório agudo (SDRA), que é a principal causa de morte em pacientes com COVID-19. METODOLOGIA: Trata-se de um estudo de revisão narrativa, o qual objetiva transcorrer sobre a eficácia do corticoide no tratamento da infecção pelo coronavírus. As buscas foram realizadas na base de dados PubMed, e foram aplicados os descritores corticosteroids e covid-19, de forma combinada. DISCUSSÃO: Existem muitas variáveis que divergem entre os autores e que influenciam no benefício do tratamento, como: dose terapêutica, período de início, seleção de um grupo de pacientes ideal e o tipo do corticoide usado. CONCLUSÃO: A partir dos estudos analisados, é possível inferir que ainda existem muitas divergências com relação ao uso de corticosteroides no tratamento da infecção pelo SARS-CoV-2. Sendo assim, são necessários novos estudos para elucidar essas questões.
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