A obesidade como fator de risco no pior prognóstico do Covid-19: uma revisão integrativa. / Obesity as a risk factor in the worst prognostic of Covid-19: an integrative review
DOI:
https://doi.org/10.34119/bjhrv4n1-292Keywords:
obesidade, Covid-19, fator de risco.Abstract
Com o surgimento do novo coronavírus, houve uma demanda de estudos para elucidar quais fatores pioram o prognóstico e aumentam a morbimortalidade dessa doença, entre eles, a obesidade. Desse modo, o presente estudo objetivou esclarecer qual o desfecho da associação dessas duas variáveis. Para tanto, foram selecionados e analisados 23 projetos de pesquisa acerca da influência da infecção por SARS-CoV2 em pacientes com obesidade. No geral, os resultados apontaram maior susceptibilidade desses pacientes em desenvolver complicações no tratamento, além de apresentarem maior tempo de internação, maior taxa de intubação e maior mortalidade. Diante disso, foram averiguados os mecanismos que atuam na piora do desfecho para esses indivíduos, entre os quais foram abordadas as particularidades imunológicas e respiratórias apresentadas por pessoas obesas e a maior prevalência da enzima conversora de angiotensina 2. Concomitantemente, ficou evidente que as demandas específicas no tratamento de pacientes com obesidade, como aparelhos adaptados, tornam o atendimento desses indivíduos ainda mais dificultoso dentro de um cenário de pandemia. Por fim, embora interferência negativa do excesso de peso tenha ficado evidente, reitera-se a necessidade de mais estudos com populações maiores e mais diversificadas, a fim de esclarecer e aprofundar todos os aspectos de interação da obesidade com o COVID-19.
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